The nosological classification (ICD-10)
Anogenital herpes simplex virus A60 infection [herpes simplex]. B00 infection, HSV [herpes simplex]. B00-B09 Viral infections characterized by skin lesions and mucous membranes. B00.2 Herpetic gingivostomatit and faringotonzillit. B00.5 Herpetic eye disease. B01 Chicken pox [varicella]. B02 Zoster [herpes zoster]. B08 Other viral infections characterized by skin lesions and mucous membranes, not elsewhere classified. B20.3 The disease caused by HIV, with manifestations of other viral infections. B25 CMV disease. B99 Other infectious diseases. D84.9 Immunodeficiency, unspecified. H16 Keratitis. Z29.1 Prophylactic immunotherapy
Application Acyclovir Ointment
Primary and recurrent herpetic lesions and mucous membranes (including genital herpes), herpes lesions in patients with immunodeficiency (treatment and prevention), herpes zoster, varicella, simple herpetic keratitis.
Dosage and administration Acyclovir Ointment
Inside, in / drip, externally and locally. Adults and children over 12 years – a / c at 5 mg / kg 3 times a day (every 8 h), with Herpes zoster in patients with impaired immune systems – 10 mg / kg every 8 hours for children from 3 months to 12 years – 5 mg / kg (250 mg/m2 body surface). Inside, adults and children over 2 years – 0.2 g of 5 times per day (excluding night) for prevention – 0.2 g 4 times a day , with shingles – by 0.8 g 4 times a day for children up to 2 years – half the adult dosage. The course of treatment usually – 5 days, with herpes zoster – 3 more days after the disappearance of the disease. Preventive treatment with organ transplants carried out within 6 ned.Pri keratite (eye ointment) – 5 times a day for 7-10 days.V If infection of the skin and mucous membranes caused by the herpes simplex virus, cream or ointment (5%) applied to the skin surface 5 times a day for 5-10 days.
Contraindications Acyclovir Ointment
Hypersensitivity.
Side effects Acyclovir Ointment
Headache, fatigue, neurological disorders, shortness of breath, nausea, vomiting, diarrhea, intestinal colic, fever, edema, lymphadenopathy, increased levels of bilirubin, urea, creatinine, transient increase in liver transaminases, and allergic reactions such as skin rash, itching. With a / in the introduction (especially in patients with impaired immunity) – agitation, confusion, lethargy, tremors, convulsions, hallucinations, psychosis, coma, reactions at the site / in the introduction – a local inflammation, phlebitis. For external use – erythema, peeling (in place of a long application of ointment), burning, burning.
Overdose Acyclovir Ointment
Symptoms include headache, neurological disorders, shortness of breath, nausea, vomiting, diarrhea, kidney failure, lethargy, convulsions, koma.Lechenie: maintaining vital functions, hemodialysis.
Precautionary measures Acyclovir Ointment
In order to prevent crystallization in tubular apparatus recommended to take plenty of fluids, adequate hydration is also necessary for I / O assignment. In cases of violations of renal excretory function and elderly persons, taking into account the dose is reduced creatinine Cl. Caution must be exercised to / in a patient with psychoneurotic disorders, renal dysfunction (and the appointment orally), liver and electrolyte disturbances, severe hypoxia.
